Reflection #1: Leticia Arreola, PharmD Candidate 2020
Dr. Elinore Chung is a medical liaison working for Regeneron Pharmaceuticals, a company that specializes in monoclonal antibodies for immunotherapy. She is also the Associate Director in immunology and inflammation. She graduated from University of Southern California with a Pharm D. Dr. Chung presents the process of drug development. She explains that drug discovery includes finding new targets. Once they find the target they will focus on, drug development continues with looking at the drug using animal models to identify toxicities, dosing. This takes about 1 to 3 years. Phase 1 determines PK/PD, healthy subjects are used in this setting. Phase 2 comprises of using the drug in diseased populations. This phase determines safety. Phase 3 consists of clinical trials for efficacy confirmation of the drug. After that is done, the drug manufacture applies for NDA & approval, then PDUFA, prescription drug use fee act, FDA states if approved or not or requirements for approval. Less than 12 % of drugs make it this far. Phase 4 is post marketing surveillance. For example this happened with Vioxx. It was approved for marketed use but during Phase 4, it was recalled. Dr. Mentions that to be qualified as a medical liaison, a person must hold an MD, PharmD or PhD. These medical liaisons with experts in their fields to form an advisory board for drug manufacturers. Medical liaisons are hired from phase 1 to 4 of drug development. I find this career very enticing. Although, there seems to be no patient contact, which I really enjoy. It does seem fulfilling when you think of developing a cancer or other disease medication that help people survive or improve their benefit of life.
Reflection#2: Alison Augustin, PharmD Candidate 2020
On April 25, 2017 Dr. Elinore S. Chung came to speak about Drug Development and Medical affairs. There are a lot of different roles in medical affairs and is critical to Drug development. There are various different departments, such as medical education, medical research, health economics/ outcomes, etc. One of the roles, Medical science liaison, is something that I recently discovered as a career path from the AMCP Night of Managed Care. They are a field- based scientific professional and was in response to the need for scientifically trained field staff to build rapport. They are the medical face of a company and they are the only medical person that a health care provider will communicate with in the company, so an MSL must have very strong social characteristics. Some of the positives working as an MSL include intellectual challenge, the ability of working remotely, working with a lot of different colleagues, and on the job learning. In this practice, the MSL must be proactive in seeking out new and updated information. This job is still emerging, but understanding the benefits and what it offers, it is a great non-traditional career path for pharmacists.