It is dosed every 4-6 hours for mild to moderate pain and has minimal GI side effects. Adults should not exceed 4g/ day to minimize liver damage, some even recommend no more than 3g/day. It is also effective for fever and is available in pediatric dosage forms.
It is effective for mild to moderate pain and has a longer duration than acetaminophen or ibuprofen. It an be given 250 mg every 8-12 hours. At OTC doses it is not anti-inflammatory and is not approved for fever.
For mild to moderate pain and is an alternate to naproxen sodium.
Dosed 200-400mg every 4-6 hours so it is less convenient to use than naproxen sodium. It is also not anti-inflammatory at OTC doses. It takes 600 to 800mg four times a day for a week on a scheduled basis to be anti-inflammatory. It may also be used for fever as an alternative to acetaminophen and is available in pediatric dosage forms. In pediatric patients be careful not to give it in children who are dehydrated from fever and diarrhea because it my be cause renal toxicity.
Here is the Pain Treatment Guideline
Posted by: Christina Duong, PharmD candidate 2015