According to the Institute of Medicine, as of 2012, over 100 million people suffer from chronic pain in the US. Many of these patients require opioid therapy to help treat their pain. In turn, addiction is a high plausibility in many of the patients that continue to take the medication after their pain has been resolved. The Center for Disease Control (CDC) reported that from 1999 to 2006 the deaths related to opioid overdoses increased by 18%. This is a devastating and threatening statistic considering that there are not any other treatment options that have proven to be superior to opioids for pain management. However, from the years 2007 to 2011 the total deaths related to opioid overdose only increased by 3%. The CDC believes that the reduction in rate of deaths could be related to two things. As of 2006, the FDA called for a more limited use of the opioid medication methadone. Methadone is a medication that is commonly used for patients that are trying to wean off of heroin addiction. In addition, the CDC believes that the reduction in the rate of deaths is linked to the recent legalization of marijuana in some states. Overall, states that have legalized marijuana have seen a reduction in opioid related deaths by 25%. Regardless of what the link to the reduction may be, this is a major step toward the right direction to control the epidemic. In addition, the DEA just announced that as of October 06, 2014, opioid medication that contain hydrocodone combinations will now be considered schedule II medications. This means that patients will only receive prescriptions for thirty-day supply and would require a new prescription in order to receive more therapy for their pain management. This new regulation is part of the effort to help curb addiction and further control the usage of opioid therapy.