First, it is important to remember that statin medications are one of the most commonly prescribed medications in the United States. In 2006, a total of 157.2 million statin prescriptions were filled. If you had to take a guess, how many people in the United States do you think have diabetes? It is a whopping total of 25.8 million people in our population. Therefore, it is important to see if statins do indeed increase the risk of getting NODM.
To assess the validity of the article, five criteria were analyzed, including dose response gradient, outcomes of cases and controls measured the same, the order of exposure versus outcome, complete and long enough follow-up, and similarity of cases and controls at baseline. Overall, the article was valid and found that being on a statin did increase risk of getting NODM. However, according to the article, the benefits of reducing risk of a MACE outweigh the risk of getting NODM. Therefore, all statin users are encouraged to continue and be compliant with their statin medication.
For more information on the presentation of the article, please see the following attachment.
Posted by: Katherine Tang, PharmD Candidate 2015